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bp0002rdr1 | Maternal Recognition of Pregnancy | REDR1990

The polypeptides and genes for ovine and bovine trophoblast protein-1

Roberts RM , Klemann SW , Leaman DW , Bixby JA , JA Cross JC , Farin CE , Imakawa K , Hansen TR

Summary. Ovine and bovine trophoblast protein-1 (oTP-1 and bTP-1) have been strongly implicated as antiluteolytic agents and responsible for maternal recognition of pregnancy in sheep and cattle, respectively. Both are interferons (IFN) belonging to the IFN-α family, but their length (172 residues versus 166 for most IFN-α) places them in an unusual subclass (the IFN-αII). The various isoforms of oTP-1 and bTP-1 produced by trophoblas...